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dc.contributor.advisorTownley, Roberten_US
dc.contributor.authorSelenke, William Michaelen_US
dc.date.accessioned2018-05-25T17:29:09Z
dc.date.available2018-05-25T17:29:09Z
dc.date.issued1970en_US
dc.identifier.urihttp://hdl.handle.net/10504/117992
dc.description.abstractPrevious papers in the literature reported the effectiveness of triacetyloleandomycin, a macrolide antibiotic, in the treatment of bronchial asthma. The beneficial effects were attributed to the antimicrobial characteristics of this compound. However, the antiasthmatic activity of the drug was found by Towniey et al. 14-18 to be retained in selected cases of asthmatics in the absence of clinically apparent or verifiable infections. | For this reason, I have undertaken to examine in animal experiments whether the anti-asthmatic activity of this and other macrolide antibiotics could be due to the possible steroid-like properties of these substances. As described below, I have concluded that the anti-asthmatic activity of these agents could be more easily explained at present by a steroid-sparing mechanism rather than by the possession of genuine steroid-like properties.en_US
dc.language.isoen_USen_US
dc.publisherCreighton Universityen_US
dc.rightsA non-exclusive distribution right is granted to Creighton University and to ProQuest following the publishing model selected above.en_US
dc.subjectMicrobiologyen_US
dc.titleNon-Antibiotic Effects of Macrolide Antibiotics of the Oleandomycin-Erythromycin Group With Special Reference to Their "Steroid-sparing" Effectsen_US
dc.typeThesis
dc.publisher.locationOmaha, Nebraskaen_US
dc.description.noteProQuest Traditional Publishing Optionen_US
dc.contributor.cuauthorSelenke, William Michaelen_US
dc.degree.levelMS (Master of Science)en_US
dc.degree.disciplineMedical Microbiology (graduate program)en_US
dc.degree.nameM.S. in Medical Microbiologyen_US
dc.degree.grantorGraduate Schoolen_US


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