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Inner Ear Hair Cell Loss and Stereocilia Defects in miR-183 Family Knockout Models
(Creighton University, 2015-05-26)
Hearing loss is the most prevalent sensory defect, and although hearing aids and cochlear implants can provide sensory input, no current therapeutic options exist for restoration of normal hearing. The microRNA-183 family ...
MicroRNAs are essential for hair cell development.
(Creighton University, 2008-10-10)
MicroRNAs are small non-coding RNAs that are processed through an endogenous biological pathway and function to post-transcriptionally regulate target gene expression. MicroRNAs affect cellular proliferation, differentiation, ...