Now showing items 1-3 of 3
Correlation of Osteoporosis and Obesity
(Creighton University, 2006-08)
Osteoporosis and obesity are two complex diseases that are prevalent in the United States. Obesity is a condition of excess body fat that exacerbates several major public health problems. Osteoporosis is a skeletal disease ...
Genetics Analysis of Bone Size Variation of Hip, Spine and Wrist in Human Pedigrees
(Creighton University, 2001-05)
Bone size is an important determinant of osteoporotic fracture. However, the importance of genetic factors in determining bone size variation is unknown. My purposes here are three-folded. 1) Estimate the heritability (h2) ...
In vivo Genome-wide Expression Study on Human Blood B cells Suggests a Novel ESRI and MAPK3 Network for Postmenopausal Osteoporosis
(Creighton University, 2007-05)
Osteoporosis is characterized by low BMD resulting from bone resorption (by osteoclasts) exceeding bone formation (by osteoblasts). In postmenopausal women, estrogen deficiency evokes increased osteoclastic activity and ...