Now showing items 1-3 of 3
Genomic Conservation of the Outer Hair Cell Motility Protein, Prestin in the Monotreme: Ornithorhyncus anatinus (Platypus)
(Creighton University, 2007-08)
The process of outer hair cell (OHC) motility, which enables sound amplification, is an active process that is thought to be unique to mammals. Prestin, the motor protein of these OHCs, is crucial for its function in ...
The Structure-Function Relationship of Prestin: from an Evolutionary Perspective
(Creighton University, 2010-10-14)
Prestin is the motor protein of cochlear outer hair cells. It belongs to a distinct anion transporter family called solute carrier protein 26A, or SLC26A. Members of this family serve two fundamentally distinct functions. ...
Studying the Atoh1 Gene Regulatory Network
(Creighton University, 2013-04)
Hearing loss due to injury of the sensory hair cells of the inner ear is largely irreversible in mammals. ATOH1, a proneural basic helix loop helix transcription factor is essential for inner ear hair cell differentiation ...